How has cancer
affected or changed your life? It took a bit longer for me to blog about this
because cancer has deeply impacted my life many years ago. My aunt who was very
close to me passed away because of cancer. Since then, I took more initiatives
to learn about this disease and hopefully that I can spread the awareness. If I
knew about Immunotherapy earlier, this treatment may help to prolong her life,
or at least reduce her sufferings. Today, I’m glad to share this piece of
knowledge that I gathered from the recent Lung Cancer and Me Blogger Workshop
and discuss about the differences between Chemotherapy and Immunotherapy.
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| Lung Cancer And Me ft Immunotherapy vs Chemotherapy Treatment |
Today I’m going share
about the scenario of Lung Cancer in Malaysia, what are the challenges of lung
cancer, and 5 Reasons Why Immunotherapy Can Help Cancer Patient. Immunotherapy
treatment is a new chapter in the cancer treatment and prognosis of cancer in
the country.
Lung Cancer in
Malaysia
Do you have family
member or friends or anyone that you know affected with lung cancer? According
to statistics lung cancer is a serious global health issue with 1.8 million of
new cases per year and 1.6 of deaths per year. In Malaysia, lung cancer is the
second most common cause of death due to cancer, accounting for 4,088 deaths per
year. And Non-Small Cell Lung Cancer (NSCLC) is the most commonly diagnosed
category of cancer, accounting for 85% of all lung cancer cases.
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| Lung Cancer in Malaysia |
These are the
symptoms of lung cancer such as persistent coughing, shortness of breath, chest
pains, fatigue, loss of appetite, and weight loss. If you suffered these
symptoms regularly for a period-of-time, please go for your diagnosis, it’s
better to prevent it. The challenges with this disease are patients tend to
ignore the symptoms until the cancer has advanced to grown, plus there are
limited treatment options over the last few decades, especially Non-Small Cell
Lung Cancer.
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| Spokesperson (from left): Dato’ Dr. Mohammed Ibrahim (Consultant Clinical Oncologist); Choo Mei Sze (Youth Ambassador, National Cancer Society Malaysia) and Kenneth Low (Assistant Manager of Health Education, Literacy, Promotion, and Policy, National Cancer Society Malaysia) |
Cancer Immunotherapy
During the workshop,
I learnt about the new break-through treatment called cancer Immunotherapy,
which is a new way of treating cancer and known as immuno-oncology. This
treatment uses the power of the body’s own immune system to prevent, control,
and eliminate cancer. Immunotherapy only targeted at the patient cancer cells,
by educating their immune system to recognize and attack specific cancer cells;
boost immune cells to help them eliminate cancer and provide the body with
additional components to enhance the immune response.
The Types of Cancer
Immunotherapy
Cancer Immunotherapy
comes in a variety of forms, including targeted antibodies, cancer vaccines,
adoptive cell transfer, tumor-infecting viruses, checkpoint inhibitors, cytokines,
and adjuvants. Some immunotherapy treatments use genetic engineering to enhance
immune cells’ cancer-fighting capabilities and may be referred to as gene
therapies.
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| Chemotherapy vs Immunotherapy |
Chemotherapy vs
Immunotherapy
My aunt went through
a few rounds of chemotherapy treatments, after each treatment she was so
drained and became weaker. It was heartbreaking to see her suffering from the side effects of chemotherapy. Today, I’m glad to be able to share and spread the
awareness about Immunotherapy treatment and the differences between
Chemotherapy and Immunotherapy.
Basically, human
cells go through different phases (cell cycle) as they form new cells. Cancer
cells form new cells more rapidly than normal cells. Chemotherapy drugs affect
cells at specific stages of a cell’s cycle. However, they do not differentiate
between cancerous cells and healthy cells.
Chemotherapy just kills all the cells being good or bad, ouchhh! Many healthy cells also have a rapid cell cycle, such as those in the gastrointestinal tract and hair follicles and thus, are more susceptible to the effects of chemotherapy resulting in nausea and hair loss during treatment.
Chemotherapy just kills all the cells being good or bad, ouchhh! Many healthy cells also have a rapid cell cycle, such as those in the gastrointestinal tract and hair follicles and thus, are more susceptible to the effects of chemotherapy resulting in nausea and hair loss during treatment.
Immunotherapy cancer
treatments use the body’s immune system to fight cancer cells by stimulating
the immune system. Immunotherapy includes treatments that work with the immune
system in different ways and works better for some types of cancer than for
others. Immunotherapy may be used by itself or with other types of treatment.
5 Reasons Why and How
Immunotherapy Can Help Cancer Patient
1. Systematic
Immunotherapy has
been an effective treatment for patients with certain types of cancer that have
been resistant to chemotherapy and radiation treatment.
As of April 2019, the
FDA has approved immunotherapies as treatments for nearly 20 cancers as well as
cancers with a specific genetic mutation.
2. Targeted
Activates immune
system to attack cancer cell specifically. Cancer researchers have discovered
some of the differences within cancer cells that enable them to thrive.
Targeted therapy refers to treatment with drugs that have been developed to
‘target’ these differences within the cell. Unlike chemotherapy, targeted
therapy drugs alter the inner workings of the cell focusing on the part of the
cancer cell that makes it different from the normal, healthy cell. Because they
leave the healthy cells alone, the side effects of targeted therapies are
different from standard chemotherapy treatments.
3. Durable
Immunotherapy offers
the possibility for long-term cancer remission. Immunotherapy can “train” the
immune system to remember cancer cells. This ‘immunomemory’ may result in
longer-lasting remissions.
Clinical studies on long-term overall survival have shown that the beneficial responses to cancer Immunotherapy treatment are durable that is, they can be maintained even after treatment is completed.
Clinical studies on long-term overall survival have shown that the beneficial responses to cancer Immunotherapy treatment are durable that is, they can be maintained even after treatment is completed.
According to Dato’
Dr. Mohammed Ibrahim, Consultant Clinical Oncologist, study showed that
survival rate of Immunotherapy patients gone up to 1/3. For cancer stage 1 and
2 can be cure and for stage 3 and 4 the treatment can control the disease from
spreading and also prolong the patients’ life.
4. Synergestic
Many immunotherapy
treatments for preventing, managing, or treating different cancers can also be
used in combination with surgery, chemotherapy, radiation, or targeted
therapies to improve their effectiveness.
5. Less Side Effects
(than other treatments)
Cancer Immunotherapy
may not cause the same side effects as chemotherapy and radiation. Cancer
Immunotherapy is focused on the immune system and is often more targeted than
conventional cancer treatments such as chemotherapy or radiation.
Both chemotherapy and radiation damage healthy cells, leading to common side effects such as hair loss and nausea/vomiting. These side effects may be less likely with immunotherapy.
Both chemotherapy and radiation damage healthy cells, leading to common side effects such as hair loss and nausea/vomiting. These side effects may be less likely with immunotherapy.
Immunotherapy can be
accompanied by side effects that differ from those associated with conventional
cancer treatments. In many cases, these side effects are tolerable and can be
reversed as long as they are addressed immediately.
Alright! I hope that
you have a better understanding about Lung Cancer in Malaysia, Chemotherapy vs
Immunotherapy, and also 5 Reasons Why and How Immunotherapy Can Help Cancer
Patient.
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